After a few ITX builds, (NCASE M1, D-Frame Mini) I was craving something a little bigger. I wanted more RAM slots, more PCI-E slots, etc. I wanted something with presence, but not unnecessarily so. Enter Cerberus X. What a little (big) case! It has a small size foot print, but with the ability to cram an E-ATX motherboard in there I was sold. I do a few LANs a year with friends and I value portability. With the handle option and its relatively small size it will be an excellent fit for my needs.
The biggest reason I went larger was the EVGA X299 Dark. I've lusted over that motherboard since I first laid eyes on it. It's so purposely built and mean looking I just had to build with one at some point. With the recent price cuts in X299 chips now was the time. Say what you will about X299, and I'll likely agree with you that Ryzen and Threadripper offer massively better price to performance ratios, but I didn't select X299 for the processors. I just had to build with the Dark.
As for the plan of attack on this build, cooling the CPU will be handled by a custom loop. This is my second custom loop as I currently run one in my D-Frame Mini. However, that one is used to cool both the CPU and GPU. The reasons I'm only going to cool the CPU via the loop are few. One, I'd like to OC the chip more this time around and I don't want it to share radiator space with the GPU. Two, I usually build every 2 years so I tend to sell my used components on craigslist or reddit. Not having to deal with selling a GPU with a water block just makes this part easier. Not everyone is going to do a loop so my potential sales market shrinks. I could see myself staying in this build longer and just upgrading the GPU down the line and this would simplify things for myself.